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It directly donates a reducing equivalent (a hydrogen electron) to these unstable molecules, neutralizing them into harmless water and oxygen before they can wreak havoc on the cell's delicate machinery

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PMID 14576844

Free radicals are unstable molecules that can cause oxidative stress, which leads to cellular damage over time

3 Metabolic reprogramming related to ferroptosis in OA Having established the significance of ferroptosis in OA pathology, we now turn our attention to how metabolic reprogramming involving lipids, amino acids, iron, and glucose underpins ferroptotic susceptibility